The link between APC and EB protein family members

APC is microtubule plus-end binding protein. APC is able to bind to microtubules directly (Munemitsu et al. 1994) and via EB1 protein (Su et al. 1995). It was also found that EB3 (member of EB1 protein family) is able to bind APCL (CNS specific homologue of APC) (Nakagawa et al. 2000).